NCT05182450

Acute Effects of Mango Leaf Extract on Cognitive Function in Healthy Adults: A Double-Blind, Placebo-Controlled Crossover Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 114 (actual)
• Sponsor: PepsiCo Global R&D · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The primary aim of this randomised, double-blind, placebo-controlled, cross-over study is to assess the short-term cognitive effects of a single dose (300 mg) of Mango Leaf Extract compared to a placebo on cognitive function, including during cognitively demanding task performance. The trial will utilise the COMPASS cognitive assessment system and cognitive demand battery (CDB), and Profile of Mood States (POMS), visual analogue mood scales (VAMS), and Stress Visual Analogue Scales (S-VAS) with assessments taking place at baseline, 30 minutes, 180 minutes and 300 minutes post treatment, on two separate testing days separated by 7 days (minimum).

Conditions

• Attention
• Cognition
• Mood

Interventions

Type	Name	Description
OTHER	Mango leaf extract capsule	Single dose
OTHER	Placebo capsule	Single dose

Timeline

• Start date: 2022-01-04
• Primary completion: 2022-06-20
• Completion: 2022-06-20
• First posted: 2022-01-10
• Last updated: 2022-11-14

Locations

1 site across 1 country: United Kingdom