NCT05181007

Drug-drug Interaction Between Ciprofol and Mefanamic Acid or Valproate

An Open-label, Two-stage Study Evaluating Drug-drug Interaction Between Ciprofol Injectable Emulsion and Mefanamic Acid or Valproate in Healthy Volunteers

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Haisco Pharmaceutical Group Co., Ltd. · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

study the effect of mefanamic acid or valproate on ciprofol

Conditions

• Drug Drug Interaction

Interventions

Type	Name	Description
DRUG	Mefanamic Acid	mefanamic acid once every 6 hours on Day 4 and Day 5, Ciprofol on Day 1 and Day 5
DRUG	Valproate	valproate once daily on Day 4 to Day 8, Ciprofol on Day 1 and Day 8

Timeline

• Start date: 2021-12-17
• Primary completion: 2022-03-23
• Completion: 2022-06-01
• First posted: 2022-01-06
• Last updated: 2022-07-14

Locations

1 site across 1 country: China

Regulatory

• FDA-regulated drug study