Trials / Completed
CompletedNCT05180279
The Impact of Circadian Misalignment on Colonic Barrier Homeostasis in Ulcerative Colitis
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 19 (actual)
- Sponsor
- Rush University Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to investigate if circadian malalignment (unusual sleeping patterns), such as night shifts (sleeping during the day and being awake during the night time), worsens the inflammation of the gut. We hope to look at patients with Ulcerative Colitis and Healthy Controls.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | 7-day sleep lab | Patients will stay in 7-day sleep lab where light exposure, diet, and activity will be closely monitored. They will have two unprepped flexible sigmoidoscopies with rectal biopsy collection and stool collection. Cycles will be shifted by 12h once on Day 3 of sleep lab and be discharged after an 8 hour sleep session on Day 7. |
Timeline
- Start date
- 2021-04-01
- Primary completion
- 2024-06-05
- Completion
- 2024-06-05
- First posted
- 2022-01-06
- Last updated
- 2025-08-19
- Results posted
- 2025-08-19
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05180279. Inclusion in this directory is not an endorsement.