Clinical Trials Directory

Trials / Completed

CompletedNCT05174715

Malnutrition Using GLIM Criteria and Comparing CT and BIA for Muscle Mass Measurement

Evaluation of Malnutrition in Patients Undergoing Major Abdominal Surgery Using GLIM Criteria and Comparing CT and BIA for Muscle Mass Measurement

Status
Completed
Phase
Study type
Observational
Enrollment
260 (actual)
Sponsor
Klinikum St. Georg gGmbH · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers

Summary

Evaluation of malnutrition with the help of the GLIM criteria. Muscle mass measurement, as recommended in the GLIM criteria was done with the help of abdominal CT scan and BIA. Both methods were compared and their association to the clinical outcome was assessed.

Detailed description

We retrospectively analysed 260 patients undergoing major abdominal surgery between January 2017 and December 2019. Patients were prospectively screened and assessed for malnutrition with Nutritional Risk Score (NRS) and Subjective Global assessment (SGA). Body composition was analysed with CT scan and BIA within 30 days before surgery. GLIM criteria were retrospectively determined referring to the Fat free Mass from BIA (FFMBIA) and Muscle Mass from axial CT scan at lumbar level 3 (MMCT). The prevalence of GLIM - malnutrition according to BIA and CT was evaluated. Multivariate logistic regression analysis was used to determine association between malnutrition and outcome parameters. ROC-curves specified sensitivity and specificity of the different tools and areas under the curve were calculated.

Conditions

Interventions

TypeNameDescription
OTHERBIAnutritional status was evaluated using BIA

Timeline

Start date
2017-01-01
Primary completion
2019-12-31
Completion
2020-07-15
First posted
2022-01-03
Last updated
2022-01-14

Source: ClinicalTrials.gov record NCT05174715. Inclusion in this directory is not an endorsement.