NCT05171842

Dissection of the Superior Mesenteric Artery

Safety and Efficacy of Endovascular Treatment in Patients With Spontaneous Isolated Superior Mesenteric Artery Dissection: a Multicenter, Prospective Single-arm Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 136 (actual)
• Sponsor: First Affiliated Hospital of Zhejiang University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the prognosis of patients with spontaneous solitary dissection of superior mesenteric artery (SIDSMA) who have been treated with stents.

Detailed description

This study is an observational study. The subject's treatment plan needs to be expected to meet the following conditions: the corresponding surgery has been completed: the femoral artery or brachial artery approach is implanted into the true lumen of the SMA bare stent (the part with a diameter ≤ 7mm is suggested to use thin-wall stent, and the part with a diameter\> 7mm It is not limited to using stents (brands) to restore the real lumen blood flow of the superior mesenteric artery. If the false cavity is large, it can be combined with a spring coil to assist embolization. Anticoagulation therapy for at least 1 day after surgery. Anticoagulation drugs are not limited to use. After discharge, the dual-antiplatelet drugs for at least 3 months, and single antiplatelet should be maintained for at least 1 year.

Conditions

• Dissection of the Superior Mesenteric Artery

Interventions

Type	Name	Description
BEHAVIORAL	Observe the prognosis after stent implantation	Observe the prognosis of patients after undergoing specific operations. Specific surgery: Use femoral artery or brachial artery to implant bare stent (stent with diameter ≤7mm is suggested to use thin-wall stent, stents with \>7mm are not restricted) to restore the blood flow of the true lumen superior mesenteric artery. If the false cavity is large, it can be combined with a spring coil to assist embolization. Anticoagulant therapy should be performed for at least 1 day after surgery. Anticoagulant drugs are not restricted. After discharge from the hospital, the dual anti-platelet drugs should be taken for 3 months, and a single anti-platelet drug should be maintained for at least 1 year.

Timeline

• Start date: 2021-09-09
• Primary completion: 2025-02-28
• Completion: 2025-02-28
• First posted: 2021-12-29
• Last updated: 2025-12-04

Locations

1 site across 1 country: China