NCT05170893

Efficacy and Safety of Coenzyme Q10 in Pediatric Hemodialysis Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 2 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

All chronic kidney disease patients, whether on regular hemodialysis or not, are at high risk of cardiovascular diseases. This is mainly due to increased oxidative stress, reduced antioxidants and generalized inflammation. Coenzyme Q10 is a vitamin-like antioxidant synthesized in almost all body cells, and it is also available in many dietary sources. It was observed that chronic kidney disease patients have low plasma levels of Coenzyme Q10. Clinical benefits of Coenzyme Q10 supplementation have been documented for various cardiovascular and neurodegenerative disorders. The investigators believe that Coenzyme Q10 supplementation may have potential benefits in pediatric patients receiving hemodialysis; mainly due to its antioxidant activity and anti-inflammatory effects.

Conditions

• Hemodialysis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Coenzyme Q10	Oral capsules
OTHER	Placebo	Oral capsules

Timeline

• Start date: 2022-01-17
• Primary completion: 2022-07-14
• Completion: 2022-07-26
• First posted: 2021-12-28
• Last updated: 2023-07-19

Locations

1 site across 1 country: Egypt