Trials / Unknown
UnknownNCT05167838
Comparative Study Between Fresh and Frozen Embryo Transfer in PCOS Patients Undergoing IVF Treatment
A Comparative Study Between Fresh and Frozen Embryo Transfer in Cases of Polycystic Ovaries Syndrome (PCOS) Patients Undergoing in Vitro Fertilization (IVF) Treatment for Infertility as Regards Clinical Pregnancy Rate and IVF Outcome
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 110 (estimated)
- Sponsor
- Cairo University · Academic / Other
- Sex
- Female
- Age
- 20 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
The objective of our study is to compare in vitro fertilization (IVF) outcomes between fresh embryo transfer (ET) and frozen-thawed ET in women with polycystic ovary syndrome (PCOS).
Detailed description
Eligible women will be randomized to two groups in a ratio of 1:1 . Both the patients and the clinicians will be aware of the allocated arm. The patients (110) will be equally randomized into two groups: Group A will undergo a day 3 fresh embryo transfer after ovarian stimulation, luteal phase support will be started just after follicular aspiration. Group B will have all of their embryo cryopreserved after ovarian stimulation with no luteal phase support after the aspiration and then undergo a frozen-thawed day 3 embryo transfer. Controlled ovarian stimulation will be done using the gonadotropin releasing hormone (GnRH) antagonist protocol then human chorionic gonadotropin( HCG) 5000 IU trigger for final oocyte maturation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | fresh embryo transfer | 55 patients undergoing fresh embryo transfer after ovarian stimulation followed by luteal phase support |
| PROCEDURE | Frozen embryo transfer | 55 patients undergoing frozen embryo transfer after ovarian stimulation followed by cryopreservation of all embryos and transfer in another cycle. |
Timeline
- Start date
- 2022-01-01
- Primary completion
- 2022-06-01
- Completion
- 2022-07-01
- First posted
- 2021-12-22
- Last updated
- 2022-04-12
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05167838. Inclusion in this directory is not an endorsement.