NCT05164445

The Role of Interventional Pulmonology, Microbiota and Immune Response in the Patient With Lung Cancer

Observational Participants Not Assigned to Intervention(s) Based on a Protocol; Typically in Context of Routine Care

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Lithuanian University of Health Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

This study is designed to evaluate complications, specificity, diagnostic yield of radial endobronchial ultrasound guided transbronchial cryobiopsy and transbronchial forceps biopsy with fluoroscopy in the diagnosis of peripheral pulmonary lesion; the interplay between non-small-cell lung cancer associated-bacteria along the gut-lung axis and immune response in the cancer microenvironment.

Conditions

• Lung Cancer

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Transbronchial forceps biopsy	All patients with peripheral lung lesion suspected of lung cancer detected on the chest computed tomography (CT) and mini probe endobronchial ultrasound (RP-EBUS) scans were enrolled. Transbronchial forceps biopsy (TBFB) was performed for all these patients.
DIAGNOSTIC_TEST	Transbronchial forceps biopsy+Transbronchial cryobiopsy	All patients with peripheral lung lesion suspected of lung cancer detected on the chest computed tomography (CT) and RP-EBUS scans were enrolled. TBFB was performed for all these patients. In addition, all of these patients, with no contraindications, underwent transbronchial cryobiopsy (TBCB)

Timeline

• Start date: 2019-09-01
• Primary completion: 2023-02-01
• Completion: 2023-08-31
• First posted: 2021-12-20
• Last updated: 2023-10-04

Locations

1 site across 1 country: Lithuania