NCT05162794

Is Laparoscopic Excision for Peritoneal Endometriosis Helpful or Harmful?

Is Laparoscopic Excision for Peritoneal Endometriosis Helpful or Harmful: A Double-blind, Randomized, Controlled, Three-armed Surgical Trial.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Aarhus · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The trial seeks to test effect of laparoscopic excision of peritoneal endometriosis on pelvic pain. Data will also be gathered on quality of life and neuropathic pain. Patients will be randomized to one of three groups: 1) laparoscopy with excision of endometrial tissue, 2) laparoscopy without excision of endometrial tissue and 3) waiting list control.

Conditions

• Endometriosis; Peritoneum

Interventions

Type	Name	Description
OTHER	Laparoscopy with excision	Diagnostic laparoscopy will be performed to visually confirm endometriosis in the peritoneum. Then, the relevant tissue will be excised and a histology will be performed.
OTHER	Laparoscopy without excision	Diagnostic laparoscopy will be performed to visually confirm endometriosis in the peritoneum. However, no tissue will be excised and histology will not be performed.
OTHER	Medical treatment-as-usual	Patients continue their hormonal and analgesic treatment-as-usual.

Timeline

• Start date: 2022-01-31
• Primary completion: 2026-01-01
• Completion: 2026-07-01
• First posted: 2021-12-17
• Last updated: 2024-11-15

Locations

5 sites across 1 country: Denmark