Clinical Trials Directory

Trials / Completed

CompletedNCT05162469

A Study of SHR-A1909 in Subjects With Advanced Malignant Tumors

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SHR-1909 Injection in Patients With Advanced Malignant Tumors

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
12 (actual)
Sponsor
Shanghai Hengrui Pharmaceutical Co., Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is an, open-label, multi-center, three-part phase I trial to evaluate the safety, pharmacokinetics and immunogenicity of SHR-1909 and preliminary anti-tumor efficacy of SHR-1909 in advanced malignant cancer.

Conditions

Interventions

TypeNameDescription
DRUGSHR-1909 injectionSHR-1909 for intravenous injection;Strength:6ml:0.3g/vial. Dose escalation (non randomized, 6 dose-levels); Dose-expansion and efficacy-expansion(non-randomized,1-3 dose-level(s)).

Timeline

Start date
2022-02-23
Primary completion
2024-03-28
Completion
2024-06-13
First posted
2021-12-17
Last updated
2025-07-28

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05162469. Inclusion in this directory is not an endorsement.