NCT05161611

Effect of Oral Zinc Sulfate on Jaundice in Neonates Admitted to Neonatal Intensive Care Unit

The Effect of Oral Zinc Sulfate on Jaundice in Neonates Admitted to Neonatal Intensive Care Unit: A Randomized, Double-Blind, Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Makassed General Hospital · Academic / Other
• Sex: All
• Age: 1 Hour – 1 Month
• Healthy volunteers: Not accepted

Summary

A randomized double-blind clinical trial will be performed in the neonatal intensive care unit of Makassed General Hospital in Beirut, Lebanon from December 2021 till August 2022. Randomized opaque envelopes to allocate the treatment will be used. The study will include neonates aged between 26 and 42 gestational weeks, who require phototherapy in the neonatal intensive care unit. Patients will be randomized into two groups.Both groups will receive standard conventional phototherapy, but the intervention group will receive 10 mg per day oral zinc sulfate until discharge.

Conditions

• Serum Bilirubin

Interventions

Type	Name	Description
DRUG	Zinc sulfate	10 mg of oral zinc sulfate will be given to neonates per day
OTHER	Placebo	10 mg of normal saline will be given to neonates per day
OTHER	Phototherapy	Neonates will be put under phototherapy

Timeline

• Start date: 2021-12-17
• Primary completion: 2022-08-28
• Completion: 2022-08-28
• First posted: 2021-12-17
• Last updated: 2022-08-30

Locations

1 site across 1 country: Lebanon