NCT05161403

The Efficacy of Hyaluronic Acid and Honey in Healing of Multiple Extraction Sockets of Primary Teeth Compared to Saline

The Efficacy of Hyaluronic Acid and Honey in Healing of Multiple Extraction Sockets of Primary Teeth Compared to Saline in a Group of Egyptian Children

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 39 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 2 Years – 7 Years
• Healthy volunteers: Accepted

Summary

This study aims to evaluate the effect of hyaluronic acid and honey compared to saline in healing of multiple extraction sockets of primary teeth in a group of children aging from Two to Seven years old.

Detailed description

A dental extraction is one of the most unpleasant experiences in children, especially for those who have undergone traumatic experiences, and this is likely to reduce future visits to the dental clinic if the treatment is not managed properly. Alveolar osteitis is one of the most common complications following dental extraction. It is considered one of the most studied complications in dentistry, and many risk factors contribute to its occurrence including being a female, young age, tobacco use, difficult or traumatic extractions, pre-existing infection, and use of vasoconstrictor in local anesthesia. Alveolar osteitis occurs during the first three days following the day of extraction, so that the socket is devoid of the blood clot, resulting in the exposure of the bare alveolar bone. Many medicines were and are still used in treating wounds, but they are somewhat expensive.

Conditions

• Wound Heal

Interventions

Type	Name	Description
DRUG	Hyaluronic acid	Wound healing is still a clinical challenge especially in patients who undergo several tooth extractions under general anesthesia or those undergoing major surgeries or those with systemic conditions that disrupt the wound healing process. use of this natural substance is a simple and cost-effective technique and is easily tolerated by children.
DIETARY_SUPPLEMENT	honey	Wound healing is still a clinical challenge especially in patients who undergo several tooth extractions under general anesthesia or those undergoing major surgeries or those with systemic conditions that disrupt the wound healing process. Use of this natural substance is a simple and cost-effective technique and is easily tolerated by children.

Timeline

• Start date: 2022-02-22
• Primary completion: 2023-09-04
• Completion: 2023-09-04
• First posted: 2021-12-17
• Last updated: 2021-12-17