NCT05159336

Transcranial Alternating Current Stimulation (tACS) for Auditory Hallucinations

Intervention Treatment of Auditory Hallucination by Transcranial Alternating Current Stimulation

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Shanghai Mental Health Center · Academic / Other
• Sex: All
• Age: 16 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Transcranial alternating current stimulation (tACS) can modulate and restore neural oscillations that are reduced in patients with psychiatric illnesses such as schizophrenia. Here, we performed a open-lable study of clinical trial in 30 schizophrenia patients with auditory hallucinations to show that tACS is effective for auditory hallucinations.

Detailed description

Each week, the patient rested quietly with her eyes open while receiving alpha-frequency tACS for 40 minutes. Stimulation was delivered at 10 Hz with 1 mA zero-to-peak amplitude in-phase to the location 1 and the location 2 acquired by the MEG technique with 5\*5 cm electrodes. A 5\* 7 cm return electrode was centered on Cz. In total, 20 weeks.

Conditions

• Schizophrenia

Interventions

Type	Name	Description
DEVICE	tACS for auditory hallucinations via single arm	a 20 weeks, weekly 40 minutes, 1mA, 10Hz-tACS protocol

Timeline

• Start date: 2021-11-16
• Primary completion: 2023-03-30
• Completion: 2023-05-28
• First posted: 2021-12-16
• Last updated: 2021-12-16

Locations

1 site across 1 country: China