NCT05159180

Development of a New Impedance Mapping System for Ablation of Atrial Arrhythmias in Patients

Desarrollo de un Nuevo Sistema de Mapeo de Impedancia Para la ablación de Las Arritmias Auriculares en Pacientes

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 15 (estimated)
• Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Precise identification of the atrial fibrosis is essential for successful catheter ablation of atrial arrhythmias in patients with atrial fibrillation. Voltage mapping of endocardial electrograms is currently used to delineate the anatomical substrate, but this is influenced by the direction of the activation wave front and is limited by the patient-specific thresholds. Mapping of local myocardial electrical impedance may overcome these limitations.

Detailed description

Clinical series: Patients with atrial arrythmias undergoing catheter ablation of these will be submitted to mapping of both voltage and tissue impedance. Likewise, the accuracy of the two maps identifying the extent of the substrate will be assesssed by gadolinium imaging. The impedance system is already constructed and certified for clinical research use.

Conditions

• Atrial Fibrillation and Flutter
• Atrial Arrhythmia
• Atrial Fibrillation Recurrent

Interventions

Type	Name	Description
DEVICE	cardioz mapping	Patients will be submitted to mapping of both voltage and tissue impedance.

Timeline

• Start date: 2021-12-13
• Primary completion: 2022-07-31
• Completion: 2022-12-31
• First posted: 2021-12-16
• Last updated: 2021-12-20

Locations

1 site across 1 country: Spain