NCT05156385

Sexual Dysfunction in Hypertensive Women

Sexual Dysfunction in Hypertensive Women According to Drug Adherence: Multicenter Cross-sectional Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 348 (estimated)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Several studies describe the existence of an association between sexual dysfunction and high blood pressure (hypertension), most often characterized by a decrease in the number of orgasms and the existence of dyspareunia. Hypertension is a contributing factor, and nonadherence to medication could amplify it. There are several ways to assess adherence to treatment: the use of declarative questionnaires, a method not without criticism because it is subject to the subjectivity of the declaration by the patient; and drug dosages, a standard technique, although insufficiently disseminated due to the high cost and greater weight of the survey protocols. Drug non-compliance is multifactorial. In addition, it has been shown that having undesirable drug effects and / or being afraid of developing them is one of the major causes of non-compliance with antihypertensive treatments. The investigators hypothesize that DS is significantly more common among hypertensive women treated with non-observers compared to hypertensive women treated with observers. The main objective is to compare the prevalence of sexual dysfunction between a group of hypertensive women treated as observers and a group of hypertensive women treated as non-observers.

Conditions

• Hypertension

Interventions

Type	Name	Description
BIOLOGICAL	Blood sample for the determination of antihypertensives or their metabolites.	15 ml of Blood sample for the determination of antihypertensives or their metabolites
BEHAVIORAL	Questionnaire on sexual activity	Questionnaire on sexual activity in women
BEHAVIORAL	Scale on hospital anxiety and depression	Scale on hospital anxiety and depression to detect anxious and depressive symptoms (14 questions)
BEHAVIORAL	Morisky Questionaire	anti-hypertensive medication compliance questionnaire

Timeline

• Start date: 2022-06-27
• Primary completion: 2026-07-07
• Completion: 2026-07-07
• First posted: 2021-12-14
• Last updated: 2024-10-23

Locations

1 site across 1 country: France