Trials / Unknown
UnknownNCT05156151
Stromal Lenticule Implantation for Management of Herpetic Stromal Keratitis
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 35 (estimated)
- Sponsor
- Eye Hospital Pristina Kosovo · Academic / Other
- Sex
- All
- Age
- 21 Years – 46 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is the evaluation of corneal transparency and improvement of visual acuity in patients with herpetic stromal keratitis.
Detailed description
Stromal keratitis is an infectious ocular disease of either necrotizing or non-necrotizing form, due to an HSV infection, and characterized by corneal stromal necrosis, inflammation, ulceration and infiltration by leukocytes. In our study these early findings suggest that the use of corneal stromal lenticules with stromal stem cells and live keratocytes could be a safe and efficient treatment for stromal scar after herpetic keratitis, and excluding the recurrence of the disease by removing the corneal scar after herpetic infection using Smile and implanting the lenticule equal to the volume of the removed scar tissue. Stromal lenticule implantation is relatively simple, low-cost and offers advantages over corneal transplantation as a definitive procedure in the treatment of this disease.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Relex-Smile |
Timeline
- Start date
- 2017-01-01
- Primary completion
- 2020-01-01
- Completion
- 2025-01-01
- First posted
- 2021-12-14
- Last updated
- 2024-02-20
Locations
1 site across 1 country: Kosovo
Source: ClinicalTrials.gov record NCT05156151. Inclusion in this directory is not an endorsement.