NCT05154682

Pain Management After Surgery

Multi-Modal Pain Management After Outpatient Orthopaedic Surgery: A Prospective Randomized Trial

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Rothman Institute Orthopaedics · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Following outpatient orthopaedic surgery, adequate pain control is imperative both for patient satisfaction and for improved recovery and rehabilitation. Opioids are frequently utilized for postoperative pain control, however they can be addictive and are known to have many deleterious effects. Recent studies have demonstrated the effectiveness of a wide variety of multi-modal postoperative pain regimens in providing adequate pain control while also decreasing opioid usage. However, the most effective multi-modal pain regimen for postoperative pain control remains unclear. This prospective, randomized study intends to investigate the efficacy of a multi-modal postoperative pain regimen compared to a traditional opioid-only pain regimen following elective outpatient orthopaedic surgery of the hand, wrist, foot, or ankle.

Conditions

• Pain, Postoperative

Interventions

Type	Name	Description
DRUG	OxyCODONE 5 mg Oral Tablet	Oxycodone will be given every 4 hours as needed for 2 weeks after surgery
DRUG	Acetaminophen 500Mg Tab	Acetaminophen will be taken every 4 hours for 2 weeks after surgery
DRUG	Naproxen 500 Mg	Naproxen will be taken every 12 hours for 2 weeks after surgery

Timeline

• Start date: 2021-11-30
• Primary completion: 2022-11-30
• Completion: 2022-11-30
• First posted: 2021-12-13
• Last updated: 2021-12-13

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study