NCT05154331

Antenatal and Postnatal Care Research Collective - Household Survey (ARCH)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 7,500 (estimated)
• Sponsor: University of North Carolina, Chapel Hill · Academic / Other
• Sex: All
• Age: 1 Day – 49 Years
• Healthy volunteers: Accepted

Summary

The overarching goal of the ARCH Survey is to establish a prospective longitudinal pregnancy surveillance study in Lusaka, Zambia, to precisely characterize the pregnancy rate and outcomes of women of reproductive age prior to, during, and following pregnancy and to investigate the structural, sociodemographic, and clinical covariates that contribute to adverse outcomes in each reproductive epoch.

Detailed description

The overall purpose of this study is to better understand the health and well-being of women before and after they become pregnant and of their infants. This information will contribute to the understanding of the health needs of women and their children, which may help doctors provide mothers and children with better care in the future. Participants in this study will be visited four times a year (every 3 months) for up to three years in total. At each visit a review of their medical records, a brief physical exam and urine pregnancy test will be conducted. Participants will also answer survey questions and self-collect vaginal swabs for future testing. We will enroll up to 5,500 women and include any infants that are born to them during their study participation.

Conditions

• Maternal Health
• Pregnancy Outcomes

Timeline

• Start date: 2022-03-29
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2021-12-13
• Last updated: 2025-05-30

Locations

1 site across 1 country: Zambia