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Active Not RecruitingNCT05150561

Muscle Dysfunction in Patients With Haematological Diseases

The Prevalence and the Prognostic Value of Sarcopenia Among Patients With Haematological Cancer Diseases - A Prospective Observational Cohort Study.

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
216 (estimated)
Sponsor
Rigshospitalet, Denmark · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

PURPOSE: To evaluate the prevalence and prognostic value of sarcopenia in patients diagnosed with hematological cancer diseases.

Detailed description

Some patients diagnosed with malignant hematological diseases are faced with poor prognosis and thus must undergo a demanding course of treatment associated with severe deconditioning potentially leading to worse prognostic outcomes. It is currently not well-described, to what extend patients body composition at the point of diagnoses should be part of standard clinical evaluation in order to optimize therapy-efficacy. Recent findings suggest that pathophysiological alterations in skeletal muscle mass and function can have significant implications for the risk of disease progression and long-term prognosis.

Conditions

Timeline

Start date
2023-10-01
Primary completion
2025-10-30
Completion
2026-05-01
First posted
2021-12-09
Last updated
2025-08-11

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT05150561. Inclusion in this directory is not an endorsement.