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UnknownNCT05150405

A Phase Ia Clinical Study of QLF31907 Injection in Patients With Advanced Malignant Tumors

An Open, Dose-escalating Phase Ia Clinical Study to Evaluate the Tolerability, Safety, Pharmacokinetics and Preliminary Antitumor Activity of QLF31907 Injection in Patients With Advanced Cancer

Status
Unknown
Phase
Phase 1
Study type
Interventional
Enrollment
54 (estimated)
Sponsor
Qilu Pharmaceutical Co., Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is designed to evaluate the safety and tolerability of QLF31907 injection, to identify the maximum tolerated dose (MTD) and dose-limiting toxicity(DLT), and determine the recommended phase Ib dose(RPIbD) and recommended phase II dose (RP2D)in patients with advanced malignant tumors.

Conditions

Interventions

TypeNameDescription
DRUGQLF31907In this study, seven dose groups were proposed. The frequency of administration was once every two weeks, and four weeks was one therapeutic cycle. The subjects will receive six cycles of QLF31907 treatment at most.

Timeline

Start date
2021-10-19
Primary completion
2024-03-31
Completion
2024-06-01
First posted
2021-12-09
Last updated
2024-01-23

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05150405. Inclusion in this directory is not an endorsement.

A Phase Ia Clinical Study of QLF31907 Injection in Patients With Advanced Malignant Tumors (NCT05150405) · Clinical Trials Directory