NCT05147454

MRI & QST Analysis in Trigeminal Neuralgia and Persistent Idiopathic Facial Pain

Assessing Somatosensory System Damage in Trigeminal Neuralgia and Persistent Idiopathic Facial Pain Through Neuroimaging and Quantitative Sensory Testing

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: Walton Centre NHS Foundation Trust · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Patients with a definite diagnosis of classical TGN and PIFP will undergo a structured clinical questionnaire and a trigeminal sensory profile using the quantitative sensory testing. Clinical measures and sensory profiles will be correlated with MRI measures.

Detailed description

Patients with a definite diagnosis of classical TGN and PIFP (according to the 2020 ICOP Classification) will undergo a structured clinical questionnaire and a trigeminal sensory profile using the quantitative sensory testing. Clinical measures and sensory profiles will be correlated with the presence and the geometry of neurovascular compression at MRI. Moreover quantitative structural neuroimaging analysis, such as trigeminal root volume, will be performed in each patient and correlated with clinical and QST data.

Conditions

• Facial Pain

Interventions

Type	Name	Description
OTHER	Quantitative Sensory Testing	Non-invasive assessment of Sensory Profile

Timeline

• Start date: 2021-11-11
• Primary completion: 2024-07-17
• Completion: 2024-07-17
• First posted: 2021-12-07
• Last updated: 2024-07-24

Locations

1 site across 1 country: United Kingdom