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Active Not RecruitingNCT05144997

Lorlatinib Continuation Study

LORLATINIB (PF-06463922) CONTINUATION PROTOCOL: AN OPEN-LABEL, SINGLE-ARM CONTINUATION STUDY FOR PARTICIPANTS WITH ALK-POSITIVE OR ROS1-POSITIVE NON-SMALL CELL LUNG CANCER (NSCLC) CONTINUING FROM PFIZER SPONSORED LORLATINIB CLINICAL STUDIES

Status
Active Not Recruiting
Phase
Phase 4
Study type
Interventional
Enrollment
76 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this protocol is to provide continued treatment access and safety follow-up for eligible participants who continue to derive a benefit from study intervention in the Pfizer sponsored lorlatinib parent studies that will be closed. Additional follow-up safety data collection will permit further characterization of the safety profile of lorlatinib in participants continuing to receive study intervention

Conditions

Interventions

TypeNameDescription
DRUGLorlatinibALK-positive NSCL treatment

Timeline

Start date
2021-12-28
Primary completion
2026-12-28
Completion
2026-12-28
First posted
2021-12-06
Last updated
2025-12-17

Locations

27 sites across 8 countries: United States, China, France, India, Japan, Singapore, Spain, Taiwan

Regulatory

Source: ClinicalTrials.gov record NCT05144997. Inclusion in this directory is not an endorsement.

Lorlatinib Continuation Study (NCT05144997) · Clinical Trials Directory