NCT05143775

Strategic Intervention on Preserving Language Function During Awake Craniotomy

Strategic Intervention on Preserving Language Function During Awake Craniotomy for Glioma Resection

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Beijing Neurosurgical Institute · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study is designed to compare the language function after traditional or a new surgical plan during awake craniotomy for glioma resection.

Detailed description

This study concentrates on patient who has type II language area glioma occupation. The investigators designed new surgical plan which is using monopolar stimulator to determine and retain the tumor margin within 5 mm from the posterior superior longitudinal fasciculus or posterior arcuate fasciculus. For the tradiitional surgical plan, the investigators use bipolar stimulator according to the current standard surgery plan. After they positive points are identified by stimulator, the positive points are retained to preserve the motor function while all the negative points of the tumor are resected. This study is to determine whether the new surgical plan is more suitable for type II language area glioma occupation.

Conditions

• Glioma

Interventions

Type	Name	Description
PROCEDURE	Awake craniotomy	Randomly select 30 participants to implement new surgical plan, which is using a monopolar stimulator to determine positive function sites and save tumors within 5 mm of the posterior superior longitudinal fasciculus/arcuate fasciculus

Timeline

• Start date: 2021-12-01
• Primary completion: 2023-12-01
• Completion: 2024-06-01
• First posted: 2021-12-03
• Last updated: 2022-01-03

Locations

1 site across 1 country: China