NCT05143762

Preemptive Dexamethasone , Paracetamol on Postoperative Period Following Adeno-tonsillectomy in Pediatric .

Effect of Preemptive Dexamethasone and Paracetamol on Postoperative Period Following Adeno-tosillectomy in Pediatric Age Group-: A Randomized Clinical Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Benha University · Academic / Other
• Sex: All
• Age: 3 Years – 16 Years
• Healthy volunteers: Accepted

Summary

Tonsillectomy is one of the most common surgical operations performed on children, and it is frequently linked with an increased risk of complications such as acute discomfort when swallowing and postoperative nausea and vomiting (PONV).The most prevalent causes for postponing discharge home are poorly managed pain and PONV.

Detailed description

Tonsillectomy is one of the most common surgical operations performed on children, and it is frequently linked with an increased risk of complications such as acute discomfort when swallowing and postoperative nausea and vomiting (PONV). The most prevalent causes for postponing discharge home are poorly managed pain and PONV. As a result, these occurrences should be avoided and managed utilizing a multimodal strategy Because of its low cost and adequate safety profile in the treatment of post-tonsillectomy pain, acetaminophen is presently regarded the fundamental analgesic in this situation. Furthermore, acetaminophen has been recommended for use in children, and its pharmacological safety in this age group has been shown. Dexamethasone is another medication that is used to reduce postoperative pain and PONV in various procedures.

Conditions

• Analgesia

Interventions

Type	Name	Description
DRUG	paracetamol	patients will receive intravenous paracetamol 30mg/kg (max 90 mg/kg/day)
DRUG	Dexamethasone	patients will receive dexamethasone 0.5mg/kg IV.
DRUG	normal Saline	patients will receive placebo 10 ml normal saline IV.

Timeline

• Start date: 2021-10-15
• Primary completion: 2022-03-01
• Completion: 2022-04-01
• First posted: 2021-12-03
• Last updated: 2022-05-09

Locations

1 site across 1 country: Egypt