Trials / Unknown
UnknownNCT05142891
Renal Tolerance of Amoxicillin and Cloxacillin Combination
Incidence of Actue Kidney Injury in Patients Treated With Amoxicillin and Cloxacillin Combination Therapy
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- University Hospital, Strasbourg, France · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
2015 European Society of Cardiology Guidelines have proposed the combination of Ampicillin and Cloxacillin for initial empirical treatment of infective endocarditis in acute severely ill patients (before pathogen identification). Yet this combination has never been studied in clinical trials. High dose penicillin treatments are associated with a risk of nephrotoxicity. The investigator's primary purpose is to describe patients treated with high dose Amoxicillin and Cloxacillin combination and to evaluate its renal tolerance.
Conditions
Timeline
- Start date
- 2021-10-15
- Primary completion
- 2022-10-01
- Completion
- 2022-10-30
- First posted
- 2021-12-03
- Last updated
- 2021-12-03
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT05142891. Inclusion in this directory is not an endorsement.