NCT05142449

Effect of Systemic Antibiotic Therapy on Postoperative Complications in Patients Undergoing Wisdom Teeth Removal Surgery.

Effect of Systemic Antibiotic Therapy on Postoperative Complications in Patients Undergoing Wisdom Teeth Removal Surgery. A Double-blind, Randomised, Placebo-controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 59 (actual)
• Sponsor: Medical University of Graz · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Not accepted

Summary

59 medically healthy patients, who are scheduled for third molar extraction surgery and give informed consent for the trial, are operated using a split-mouth technique. One group of patients will be assigned to the test group (Amoxilan) for the first surgery and to the control group (placebo) for the second surgery, and vice versa, according to randomisation. Patients receive 8 capsules Amoxilan or placebo (according to randomisation) perioperatively, and 6 capsules Amoxilan/placebo per day for 3 days postoperativeley.

Conditions

• Third Molar Extraction Surgery

Interventions

Type	Name	Description
DRUG	Amoxilan	Patients receive 8 capsules Amoxilan perioperatively and for the next 3 days 6 capsules per day
OTHER	Placebo	Patients receive 8 capsules placebo perioperatively and for the next 3 days 6 capsules per day

Timeline

• Start date: 2019-03-25
• Primary completion: 2022-09-01
• Completion: 2022-09-01
• First posted: 2021-12-02
• Last updated: 2022-10-10

Locations

1 site across 1 country: Austria