NCT05142020

Biomarkers for Early Screening of Gestational Diabetes Mellitus

Study on Early Screening Biomarkers of Gestational Diabetes Mellitus and Its Related Pathogenesis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 480 (estimated)
• Sponsor: Women's Hospital School Of Medicine Zhejiang University · Academic / Other
• Sex: Female
• Age: 20 Years – 49 Years
• Healthy volunteers: Accepted

Summary

Gestational Diabetes Mellitus (GDM) refers to the abnormal glucose metabolism first detected during pregnancy. It is estimated that approximately 7% of pregnant women worldwide and their offspring are affected by GDM. The incidence of GDM in China is as high as 18.9%. A number of studies have shown that GDM complicates 3%-25% of pregnancies and poses serious health and life threats to the mother and child. In fact, due to the lack of physical activity during pregnancy and the decrease of insulin sensitivity compared with non-pregnancy, the optimal time for intervention has long been lost until the diagnosis of GDM in the second trimester. However, it is a pity that no authoritative screening method for GDM in early pregnancy has been established, and the pathogenesis of GDM is still unclear. This study intend to search for biomarkers used for screening of GDM in early pregnancy and explore the pathogenesis of GDM, so as to provide new ideas for prevention measures and treatment targets of GDM.

Conditions

• Gestatiaonl Diabetes Mellitus
• Early Pregnancy

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-08-22
• Completion: 2023-12-31
• First posted: 2021-12-02
• Last updated: 2023-02-01

Locations

1 site across 1 country: China