Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05140148

Promoting Recovery After STroke With Amantadine

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
60 (estimated)
Sponsor
University of Pennsylvania · Academic / Other
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

The investigators aim to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial (RCT). Patients will be randomized post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine arm. Patients will be on study drug or placebo for 1 month but will be enrolled for 3 months total. At various time points patients will be examined and fill out questionnaires to determine level of stroke recovery.

Conditions

Interventions

TypeNameDescription
DRUGAmantadineAmantadine is a antiviral drug and dopamine promoter that is currently approved by the FDA for the treatment of influenza A and Parkinson's Disease
DRUGPlaceboplacebo pills

Timeline

Start date
2022-02-01
Primary completion
2027-12-31
Completion
2028-06-30
First posted
2021-12-01
Last updated
2026-03-30

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05140148. Inclusion in this directory is not an endorsement.