NCT05139875

Comparing Intra-articular Betamethasone (Diprospan) and Triamcinolone Acetonide Injection in Knee Osteoarthritis

A Comparative Study of Betamethasone (Diprospan) and Triamcinolone Acetonide as Single Intra-Articular Injection in Knee Osteoarthritis, A Double-Blinded, Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 105 (actual)
• Sponsor: Thammasat University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the efficacy of Intra-articular corticosteroid injection between Betamethasone (Diprospan) and Triamcinolone acetonide for treatment of knee osteoarthritis

Detailed description

After being informed about the study and potential risks, all patients giving written informed consent will be chosen for eligibility for the study entry. At day 0 (before intra-articular injection), patients who meet the eligibility criteria will be randomized in a double-blind manner (participant and investigator) in a 1:1 ratio to Betamethasone (Diprospan 1 ml) or Triamcinolone acetonide (40 mg) single intra-articular injection

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
DRUG	Betamethasone Dipropionate / Betamethasone Sodium Phosphate	Single intra-articular Betamethasone Dipropionate / Betamethasone Sodium Phosphate (Diprospan) injections to affected knee
DRUG	Triamcinolone Acetonide 40mg/mL	Single intra-articular Triamcinolone Acetonide injections to affected knee

Timeline

• Start date: 2022-01-01
• Primary completion: 2024-04-30
• Completion: 2024-04-30
• First posted: 2021-12-01
• Last updated: 2024-08-30

Locations

1 site across 1 country: Thailand