Trials / Recruiting
RecruitingNCT05139784
BeAT1D: Benign Autoimmunity and Type 1 Diabetes
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 740 (estimated)
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France · Other Government
- Sex
- All
- Age
- 1 Year
- Healthy volunteers
- Accepted
Summary
National multi-center non-interventional case-control cohort study with collection of biological samples to characterize the autoimmune T and B lymphocytes involved in the development of type 1 diabetes.
Detailed description
The overall objective of this study is to define the differential characteristics of autoimmune T and B lymphocytes across individuals with T1D, other forms of diabetes or autoimmunity, and no disease. The hypothesis is that the characterization of the autoimmune T and B lymphocytes involved in T1D development may allow us to clarify the pathophysiological mechanisms of disease and to identify novel biomarkers for diagnostic, prognostic and therapeutic follow-up applications.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Biosampling | Collection of blood and stool specimens; and collection of lymph node specimens for the group undergoing surgical lymphadenectomy. |
Timeline
- Start date
- 2022-10-24
- Primary completion
- 2027-12-01
- Completion
- 2027-12-01
- First posted
- 2021-12-01
- Last updated
- 2025-05-16
Locations
17 sites across 1 country: France
Source: ClinicalTrials.gov record NCT05139784. Inclusion in this directory is not an endorsement.