NCT05139329

The ORCHESTRATE-Myocarditis Registry

Observational Registry of Ischemia Negative Chest Pain as the Presentation of Underlying Myocarditis: the ORCHESTRATE-Myocarditis Registry

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 382 (estimated)
• Sponsor: Kansas City Heart Rhythm Research Foundation · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A retrospective, observational study consisting of patients who presents with typical/atypical chest pain and have an ensuing negative ischemic evaluation

Detailed description

Multicenter, retrospective, observational study consisting of patients who presents with typical/atypical chest pain to the emergency department and have an ensuing negative ischemic evaluation. Planned to review the subsequent diagnostic process in these patients, including patients with CMRI (Cardiac Magnetic Resonance Imaging), PET (Positron Emission Tomography) imaging for evaluation of myocarditis with the goal of quantifying the number of patients who go on to have a proven diagnosis of myocarditis that can explain their presenting symptoms.

Conditions

• Myocarditis
• Ischemia
• Chest Pain

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Imaging	To better understand the prevalance of further imaging for evaluation of myocarditis, all patients with negative workup will be included and see what number of patients undergo further CMRI, FGD-PET, or speckle tracking echocardiography. Patients will then be categorized as those with myocarditis with positive diagnosis, negative diagnosis or unknown.

Timeline

• Start date: 2026-01-01
• Primary completion: 2026-03-01
• Completion: 2026-05-01
• First posted: 2021-12-01
• Last updated: 2025-08-28

Locations

4 sites across 1 country: United States