NCT05137808

Understanding Blood Pressure Changes After Birth

A Prospective Cohort Study, Understanding Blood Pressure Changes in the Immediate Twelve Weeks Postpartum for Women Who Had a Hypertensive Disorder in Pregnancy and How Existing Care Pathways Identify and Monitor Women at Risk of Cardiovascular Disease

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: St George's, University of London · Academic / Other
• Sex: Female
• Age: 16 Years
• Healthy volunteers: —

Summary

Research Question How does maternal blood pressure respond in the postpartum period for women who had a hypertensive disorder in pregnancy? Aim To evaluate the recovery of maternal blood pressure after a pregnancy affected by new onset hypertension after twenty weeks gestation Objectives * To identify rates of persistent hypertension after pregnancies affected by HDP * To assess and compare the accuracy of HBPM against the gold standard of ABPM * To assess the maternal acceptance of HBPM and ABPM * To explore what CVD-related care information is provided at the 6-8 week GP appointment

Detailed description

This research aims to investigate how women's blood pressure responds after birth and assess the time it takes to return to normal ranges. This will be calculated by participants undertaking three consecutive days of home blood pressure monitoring, every fortnight from two until twelve weeks postpartum. At twelve weeks postpartum, women will have a twenty-four ambulatory blood pressure assessment. This will highlight the prevalence of persistent high blood pressure and how often GPs will need to monitor women's blood pressure in the immediate few weeks after birth. Women will be asked to complete a questionnaire after their six to eight week GP appointment, assessing if women recall having their blood pressure checked and/or the risks of heart disease explained to them and if they received any lifestyle advice to reduce these risks. Women will be asked to complete a second questionnaire at twelve weeks postpartum assessing their acceptance and preference of home and twenty four hour blood pressure monitoring. This research aims to identify any gaps in the current care of women in the postnatal period and use this information to provide better quality of care to women so they can lead healthier lives and reduce their risk of heart disease.

Conditions

• Hypertension in Pregnancy

Timeline

• Start date: 2022-05-09
• Primary completion: 2023-08-31
• Completion: 2023-12-31
• First posted: 2021-11-30
• Last updated: 2022-05-20

Locations

1 site across 1 country: United Kingdom