Clinical Trials Directory

Trials / Completed

CompletedNCT05134935

Defocus (DIMS) Spectacles Versus Ortho-K Lenses (OKL) for Slowing Myopia Progression in Children Aged 6-12 Years.

Defocus Incorporated Multiple Segment (DIMS) Spectacle Lenses Versus Orthokeratology Lenses (OKL) for Slowing Myopia Progression In Children Aged 6-12 Years. A Non-inferiority Randomized Clinical Trial. The NISDO Study.

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
90 (actual)
Sponsor
Vejle Hospital · Academic / Other
Sex
All
Age
6 Years – 12 Years
Healthy volunteers
Not accepted

Summary

The goal of this non-inferiority randomized clinical trial is to compare the myopia control efficacy of Ortho-K lenses (OKL) and Defocus (DIMS) spectacles in myopic children aged 6-12 years. The main question it aims to answer is: \- Is the DIMS spectacle lens not worse than the OKL after 18 months of therapy? The participants are randomly assigned to either OKL or DIMS spectacles and followed during 18 months of therapy.

Conditions

Interventions

TypeNameDescription
DEVICEDefocus Incorporated Multiple Segment (DIMS) Spectacles18 months of therapy.
DEVICEOrthokerathology lenses (OKL)18 months of therapy.

Timeline

Start date
2022-06-29
Primary completion
2025-12-02
Completion
2025-12-02
First posted
2021-11-26
Last updated
2026-01-07

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT05134935. Inclusion in this directory is not an endorsement.