NCT05134558

Xenon-enhanced Ventilation CT-guided Radiotherapy for Lung Cancer Treatment

Xenon-enhanced Ventilation CT-guided Radiotherapy for Lung Cancer Treatment: Functional Protection of the Lung and Prevention of Radiation Pneumonitis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The investigators aim to use xenon-enhanced ventilation computed tomography (CT) to design personalized functional lung avoidance radiotherapy for lung cancer patients who are scheduled to receive lung radiation therapy. The investigators' goal is to optimally protect the lung function of the patients and reduce the incidence of radiation pneumonitis.

Detailed description

There has been an increase in the application of radiation therapy in the treatment of lung tumors; however, the associated side effect, called radiation pneumonitis, can significantly reduce lung function and the quality of life of patients, eventually leading to fatal consequences. The investigators aim to use xenon-enhanced ventilation computed tomography (CT) to design personalized functional lung avoidance radiotherapy for lung cancer patients who are scheduled to receive lung radiation therapy. The investigators' goal is to optimally protect the lung function of the patients and reduce the incidence of radiation pneumonitis.

Conditions

• Lung Cancer
• Radiation Therapy Complication

Interventions

Type	Name	Description
RADIATION	Xenon-enhanced Ventilation CT-guided Radiotherapy	Xenon-enhanced Ventilation CT-guided Radiotherapy for functional protection of the lung

Timeline

• Start date: 2020-02-04
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2021-11-26
• Last updated: 2021-11-26

Locations

1 site across 1 country: Taiwan