Trials / Completed
CompletedNCT05134350
Study of the Effect of Food and a Proton Pump Inhibitor (PPI; Omeprazole) on LOXO-305 in Healthy Participants
A Phase 1, Open Label, Randomized, 2-Way Crossover, 3-Period Study to Evaluate the Effect of Food and a Proton Pump Inhibitor on the Pharmacokinetics of LOXO-305 in Healthy Adult Subjects
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 10 (actual)
- Sponsor
- Loxo Oncology, Inc. · Industry
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
The main purpose of this study is to learn about how food and a PPI (omeprazole) affect LOXO-305 in healthy participants. Participation could last about nine weeks.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | LOXO-305 | LOXO-305 orally. |
| DRUG | Omeprazole | Omeprazole Orally. |
Timeline
- Start date
- 2020-02-06
- Primary completion
- 2020-03-23
- Completion
- 2020-03-23
- First posted
- 2021-11-24
- Last updated
- 2025-01-10
- Results posted
- 2025-01-10
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT05134350. Inclusion in this directory is not an endorsement.