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Active Not RecruitingNCT05130827

Study of Plinabulin and Pegfilgrastim in People With Multiple Myeloma Undergoing an Autologous Hematopoietic Stem Cell Transplant (AHCT)

Pilot Trial of Plinabulin and Pegfilgrastim to Reduce the Duration of Absolute Neutropenia After Autologous Hematopoietic Cell Transplantation for Patients With Multiple Myeloma

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
17 (actual)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study will see how long it takes for white blood cell counts to return to normal in people with multiple myeloma (MM) who receive plinabulin and pegfilgrastim after undergoing an autologous hematopoietic stem cell transplant (AHCT).

Conditions

Interventions

TypeNameDescription
DRUGPlinabulin40mg flat dose IV infusion, infused over approximately 30 minutes starting between 1-3 hours after stem cell infusion on day 0.

Timeline

Start date
2021-12-21
Primary completion
2026-11-01
Completion
2026-11-01
First posted
2021-11-23
Last updated
2025-12-24

Locations

7 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05130827. Inclusion in this directory is not an endorsement.

Study of Plinabulin and Pegfilgrastim in People With Multiple Myeloma Undergoing an Autologous Hematopoietic Stem Cell T (NCT05130827) · Clinical Trials Directory