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Trials / Withdrawn

WithdrawnNCT05130086

A Study of Islatravir (MK-8591) in Trans and Gender Diverse Participants (MK-8591-035)

A Phase 2 Open-Label Study to Evaluate the Safety and Pharmacokinetics of Oral Islatravir Once-Monthly in Trans and Gender Diverse Individuals on Gender-Affirming Hormone Therapy and at Low-Risk for HIV-1 Infection

Status
Withdrawn
Phase
Phase 2
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The primary objective of this study is to evaluate the safety and tolerability of Islatravir (ISL) in trans and gender diverse (TGD) participants who are receiving gender-affirming hormone therapy (GAHT) and are at low-risk for human immunodeficiency virus 1 (HIV-1) infection.

Conditions

Interventions

TypeNameDescription
DRUGIslatravir60 mg Islatravir taken orally in tablet form once monthly for up to 24 weeks

Timeline

Start date
2022-10-17
Primary completion
2024-03-25
Completion
2024-03-25
First posted
2021-11-22
Last updated
2022-10-17

Regulatory

Source: ClinicalTrials.gov record NCT05130086. Inclusion in this directory is not an endorsement.

A Study of Islatravir (MK-8591) in Trans and Gender Diverse Participants (MK-8591-035) (NCT05130086) · Clinical Trials Directory