NCT05129774

Chemoradiotherapy Sequenced Radical Surgery for Colorectal Cancer With PALNM

Concurrent Chemoradiotherapy Sequenced Radical Surgery for Para-aortic Lymph Node Metastasis of Left-sided Colon and Rectal Cancer

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Qilu Hospital of Shandong University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

In left-sided colon and rectal cancer, the occurrence of synchronous para-aortic lymph node metastasis is rare, with the incidence of being approximate 1-2%. Currently, there has been no standard treatment strategy for this situation. The present trial is designed to evaluate the safety and efficacy of para-aortic lymph node dissection for left-sided colon and rectal cancer with synchronous para-aortic lymph node metastasis

Conditions

• Colorectal Neoplasms Malignant
• Lymph Node Excision
• Chemoradiotherapy

Interventions

Type	Name	Description
PROCEDURE	Radical surgery with PALND	sufficient resection margins of the tumor, D3 dissection of the regional lymph nodes and para-aortic lymph node dissection from the bifurcation of iliac artery to the left renal vein via laparoscopic approach
PROCEDURE	Radical surgery without PALND	surgery includes sufficient resection margins of the tumor and D3 dissection of the regional lymph nodes without PALND

Timeline

• Start date: 2022-01-01
• Primary completion: 2024-01-01
• Completion: 2027-01-01
• First posted: 2021-11-22
• Last updated: 2021-11-22

Locations

1 site across 1 country: China