NCT05127928

Antioxidants Vitamins and Muscle Damage

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Universidad Europea de Madrid · Academic / Other
• Sex: All
• Age: 18 Years – 33 Years
• Healthy volunteers: Accepted

Summary

Determine if acute supplementation with antioxidant vitamins (vitamin C and vitamin E) influences the muscle damage and fatigue caused after an acute session of eccentric training.

Detailed description

A randomized, single-blind, placebo-control parallel trial will be conducted. In a previous session volunteers will be interviewed to determine if they meet the inclusion criteria. Participants should avoid ingesting of foods that contain high amounts of antioxidant compounds: more than two juices of fruits, more than four cups of coffee or tea. Juices with high antioxidant content should be avoided. Alcoholic beverages should also be avoided. Participants will be divided in to groups and will performance one resistance exercise sessions. Prior to exercise, one group will intake supplementation VitC (1000 mg) + VitE (235 mg) and the other supplementation with placebo. The following sequence will be performed in each session: 1) baseline assessment (analysis of the composition body, blood draw and parameters of performance) prior to exercise session ; 2) administration of vitamin or placebo supplementation 2 hours before exercise session ; 3) post-exercise assessments (blood biomarkers and performance parameters) immediately after the session and after 24 hours. DOMS will also be assessed 48 h and 72 h after training. The training session implemented will be designed by a Sport Scientific

Conditions

• Oxidative Stress

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Dietary Supplement: Vitamin C and vitamin E	Antioxidant supplementation
DIETARY_SUPPLEMENT	Placebo	Placebo administration

Timeline

• Start date: 2022-02-10
• Primary completion: 2022-02-15
• Completion: 2022-03-06
• First posted: 2021-11-19
• Last updated: 2022-04-07

Locations

1 site across 1 country: Spain