NCT05122169

Skip Prep of Vaginal Delivery to Prevent Puerperal / Perinatal Infection in Vaginal Delivery

Establishment of Clinical Practice Guideline to Prevent Puerperal / Perinatal Infection in Vaginal Delivery for Pregnant Women and Newborns

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 4,140 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: Female
• Age: 19 Years
• Healthy volunteers: Accepted

Summary

This is a multi-center, randomized, controlled trial study to find whether use of chlorhexidine-alcohol or povidone-iodine for pre-vaginal delivery skin prep is superior to reduce postpartum infection in pregnant women with vaginal delivery. The primary outcome is the episiotomy site infection.

Conditions

• Vaginal Delivery
• Surgical Site Infection

Interventions

Type	Name	Description
DRUG	Povidone-Iodine	Skin preparation with povidone-iodine pre-vaginal delivery skin preparation.
DRUG	Chlorhexidine	Skin preparation with chlorhexidine-alcohol pre-vaginal delivery skin preparation.

Timeline

• Start date: 2021-12-01
• Primary completion: 2025-12-31
• Completion: 2026-05-31
• First posted: 2021-11-16
• Last updated: 2021-11-26