NCT05121090

Lille Study for Childhood Health Promotion

Prevention of Child Obesity: an Interventional Study of a Personalized Multidisciplinary Care Efficacy in Children of Primary School

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 460 (estimated)
• Sponsor: University Hospital, Lille · Academic / Other
• Sex: All
• Age: 5 Years – 6 Years
• Healthy volunteers: Accepted

Summary

Obesity could be avoided but once declared it become a chronic disease with numerous health complications, including cardiovascular and metabolic diseases, cancers, and finally a loss of life expectancy. Considering that after the age of 6 years old, half of the obese children will become obese adults, the WHO has been declared childhood obesity prevention as a health priority area. Large-scale prevention of obesity is challenging and it would be more efficient to proceed to early identification of high risks children to implement personalized prevention. The ELIPSE study main objective is to evaluate the efficacy of personalized multidisciplinary care to reduce the BMI of overweight or obese children. A 2 years educational program will be evaluated at short and longer terms (after a 12 months follow-up), and its benefits will also be assessed based on comparison with a historical control group. Along with efficacy evaluation, scientific objectives were designed to investigate clinical, genetic, social, and behavioural risk factors and to analyse potential correlations between these factors and a predisposition to overweight or obesity. Moreover, advanced analyses will be performed to decipher the impact of diverse risk profiles on the efficacy of the educational program. The motive of the ELIPSE study is to promote the health and well-being of children and their families to tackle the health burden represented by childhood overweight and obesity. Combined with innovative scientific objectives, this study ambitions to develop more efficient and more personalized preventive care methods.

Conditions

• Overweight, Infant
• Overweight and Obesity
• Overweight, Childhood

Interventions

Type	Name	Description
BEHAVIORAL	Educational program	The educational program is based on dietary, physical activity, psychology, and sophrology approaches dispensed by health care professionals. Evaluations will consist of anthropometric measurements (height, weight, body mass index), behavioural questionnaires, and basic physical tests (handgrip, squats, balance, …). Optionally, a saliva collection will be proposed to obtain the DNA required for genetic analyses.

Timeline

• Start date: 2022-01-19
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2021-11-16
• Last updated: 2026-04-07

Locations

1 site across 1 country: France