NCT05120492

Optimal Management of Extreme Obesity and Severe Knee Osteoarthritis Feasibility Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Nova Scotia Health Authority · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Does weight loss surgery in patients with morbid obesity prior to knee replacement surgery improve outcomes from knee replacement surgery

Detailed description

RCT involving patients who have severe knee osteoarthritis and have a body-mass index (BMI; the weight in kilograms divided by the square of the height in meters) of 45 to 60 and are randomly assigned to receive dietary and lifestyle counseling for 9 to 13 months followed by total knee replacement (control arm) or sleeve gastrectomy with dietary and lifestyle counseling for 9 to 13 months followed by total knee replacement (treatment arm).

Conditions

• Knee Osteoarthritis
• Morbid Obesity

Interventions

Type	Name	Description
PROCEDURE	bariatric surgery followed by total knee replacement	The only intervention is the randomization of the priority of the 2 procedures.

Timeline

• Start date: 2022-04-22
• Primary completion: 2027-07-01
• Completion: 2027-07-01
• First posted: 2021-11-15
• Last updated: 2024-08-21

Locations

1 site across 1 country: Canada