NCT05117437

The Effect Of Anaerobic Exercise On Bone Morphogenetic Protein 9

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 81 (actual)
• Sponsor: Ege University · Academic / Other
• Sex: Male
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Bone morphogenetic protein (BMP) 9 from the BMP family has an important role in the remodeling of bone and cartilage. Due to these features, BMP9 can play an important role in especially anaerobic exercise training adaptations. However, the role of anaerobic exercise in these effects is still unclear. The aim of this study is to investigate the role of BMP9 on the effects of acute and chronic anaerobic exercise on bone metabolism markers. Postprandial venous blood samples were taken pre- and post- acute YOYO intermittent recovery test (level 1) in 40 trained male athletes aged 18-35 who did anaerobic sports (such as basketball, volleyball and handball) and 41 sedentary volunteers aged 18-35. Serum BMP9, as markers of bone formation and resorption; alkaline phosphatase (ALP), C-terminal telopeptide of type 1 collagen (CTX1), cartilage oligomeric matrix protein (COMP) and calcium levels were determined. The data to be obtained as a result of our study can give information about the relationship between the skeletal and bone health of the athletes and anaerobic exercise.

Conditions

• Healthy
• Exercise

Interventions

Type	Name	Description
OTHER	Physiological test	This test was conducted to determine the endurance levels of the participants.
OTHER	Physical test	Height, weight, and BMI were determined
OTHER	Biochemical tests	BMP9, CTX1, COMP, oxLDL protein levels, ALP, GGT, TAS, TOS, OSI, NO, calcium, T-C, LDL-C, Triglyceride, HDL-C, glucose, CRP, AST, ALT, erythrocyte, mean erythrocyte volume (MCV), hematocrit, leukocyte, thrombocyte levels were determined from blood samples.

Timeline

• Start date: 2020-12-03
• Primary completion: 2021-06-01
• Completion: 2021-12-01
• First posted: 2021-11-11
• Last updated: 2021-11-11

Locations

1 site across 1 country: Turkey (Türkiye)