NCT05116436

Genetic Study of Idiopathic Scoliosis in a Cohort of Families (SCOGEN)

Genetic Study of Idiopathic Scoliosis in a Cohort of Families

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 43 (estimated)
• Sponsor: Ramsay Générale de Santé · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study will focus on a large cohort of multiplex families, to precisely identify candidate genes. The fact of have a large database (fifty families, collected by the principal investigator for more than two decades), will contribute to the discovery of genes of interest. It will also allow testing for the presence or absence of mutations found in other cohorts in previous studies. The main objective of this study is to identify genetic abnormalities associated with the presence and severity of idiopathic scoliosis, in families of scoliosis.

Conditions

• Scoliosis Idiopathic

Interventions

Type	Name	Description
PROCEDURE	Blood sample	It will test the presence or absence of genetic mutations found in other cohorts in previous studies.
PROCEDURE	Spine X-ray	To determine the scoliosis

Timeline

• Start date: 2020-06-06
• Primary completion: 2021-06-06
• Completion: 2022-06-06
• First posted: 2021-11-11
• Last updated: 2021-11-11

Locations

1 site across 1 country: France