NCT05115721

Establishing the Reference Interval for Pulse Oxygen Saturation in Neonates at High Altitude

A Prospective Study on Establishing the Reference Interval for Pulse Oxygen Saturation in Neonates at High Altitude

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 10,000 (estimated)
• Sponsor: Nanjing Medical University · Academic / Other
• Sex: All
• Age: 24 Hours – 28 Days
• Healthy volunteers: Accepted

Summary

The now widely used reference interval for pulse oxygen saturation of the neonate after 24 hours of birth has been developed relying on data from low altitude.It is not suitable for neonates at high altitude. At present, no reference interval has been established at high altitude, and the existing studies have many limitations. So this study was designed.

Detailed description

Knowledge of the reference interval of pulse oxygen saturation (SpO2) in neonates is crucial for accurate identification of neonatal hypoxemia. The now widely used standard was derived from low altitude data, which is not suitable neonates at high altitude. At present, many scholars have paid attention to this problem. But, previous studies still have some limitations. For example, they often only focus on a specific altitude. However, with the increase of altitude, the pulse oxygen saturation decreases in a curve, so their study results are only suitable for this specific altitude and can not be widely used.

Conditions

• High Altitude

Interventions

Type	Name	Description
OTHER	no intervention	It's only observational study. No interventions.

Timeline

• Start date: 2022-02-01
• Primary completion: 2023-02-01
• Completion: 2023-02-10
• First posted: 2021-11-10
• Last updated: 2022-03-03

Locations

1 site across 1 country: China