NCT05114304

Prevalence of Mood and Anxiety Disorders in Adult Patients With Pulmonary Langerhans Cell Histiocytosis

Prevalence of Mood and Anxiety Disorders in Adult Patients With Pulmonary Langerhans Cell Histiocytosis: an Exploratory Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Pulmonary Langerhans cell histiocytosis (PLCH) is a rare disease, of unknown etiology, that occurs almost exclusively in smokers.The clinical experience suggests a high prevalence of anxiety symptoms and an addictive profile. However, no study to date has precisely investigated the prevalence of co-morbid psychiatric disorders in this population.The aim of the study is to evaluate the prevalence of co-morbid psychiatric disorders in adult PLCH patients. This study should allow: * to assess the prevalence of psychiatric disorders co-morbid in PLCH patients * a targeted and more effective management of patients * a better response rate to smoking and cannabis weaning, that represents a major goal for these patients.

Conditions

• Pulmonary Langerhans Cell Histiocytosis

Interventions

Type	Name	Description
OTHER	Evaluation of co-morbid psychiatric disorders	Added scales : * Mini Internationnal Neuropsychiatric Interview * Fagerström test * DSM-5 Scale Additional dosage : - a urine sample will be taken to evaluate the presence of tobacco and nicotine breakdown products and the presence of various toxics Expired carbon monoxide for patients using nicotine substitutes

Timeline

• Start date: 2021-11-01
• Primary completion: 2022-11-01
• Completion: 2022-11-01
• First posted: 2021-11-09
• Last updated: 2021-11-09

Locations

1 site across 1 country: France