NCT05112016

Long-term Cohort Study of Mesorectal Excision for Rectal Cancer

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 250 (estimated)
• Sponsor: Kantonsspital Winterthur KSW · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this cohort study is to record, evaluate and compare the surgical, oncological as well as the functional outcome and Quality of life after mesorectal excision for rectal cancer

Detailed description

Outcomes of mesorectal excision patients will be analysed. Medical records will be reviewed and perioperative outcomes retrieved, incl. long-term oncological and functional/quality of life data. A retrospective cohort over 10 years (2007-2016) will serve as a control to a prospective cohort over 10 further years (2017-2026) as to investigate trends in perioperative and oncological outcomes (min. follow-up of 5 years + adequate cohort size). Prospective data on bowel function, urogenital function and quality of life will measured at time of diagnosis and further. Variations in neoadjuvant/adjuvant treatment and surgical approaches will be assessed for their effect on the outcomes of interest.

Conditions

• Rectum
• Cancer

Interventions

Type	Name	Description
PROCEDURE	Total mesorectal excision for rectal cancer

Timeline

• Start date: 2007-01-01
• Primary completion: 2026-12-31
• Completion: 2028-07-31
• First posted: 2021-11-08
• Last updated: 2021-11-08

Locations

1 site across 1 country: Switzerland