NCT05111028

Reversal of Aspirin Antiplatelet Therapy With Cold Stored Platelets

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Bloodworks · Academic / Other
• Sex: All
• Age: 18 Years – 59 Years
• Healthy volunteers: Accepted

Summary

Purpose of this study is to compare the reversal responses of 4°C cold stored platelets (CSP) versus 7 day, 22°C room temperature stored platelets (RTP) when given to healthy adult subjects who have received a loading dose of aspirin antiplatelet therapy.

Conditions

• Reversal of Platelet Aggregation Inhibitors

Interventions

Type	Name	Description
BIOLOGICAL	Autologous Room Temperature stored Platelet transfusion	An autologous transfusion of platelets stored at 22°C for 7 days.
BIOLOGICAL	Autologous Cold Stored Platelet transfusion	An autologous transfusion of platelets stored at 4°C for 7, 14, 21, or 28 days.

Timeline

• Start date: 2020-11-20
• Primary completion: 2021-11-01
• Completion: 2021-11-01
• First posted: 2021-11-08
• Last updated: 2021-11-08

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study