NCT05110040

Multi-model Image of Immunosuppressive Agents in TAO

A Multi-model Image of Immunosuppressive Agents in Thyroid Associated Ophthalmopathy.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (estimated)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the efficacy of immunosuppressive agents treating Thyroid Associated Ophthalmopathy by multi-model image.

Detailed description

Thyroid Associated Ophthalmopathy is one of autoimmune orbital diseases characterized by enlargement of the extraocular muscles and increase in fatty or/and orbit connective tissue volume affecting the appearance and visual function of the eyes. TAO can be classified into active phase and inactive phase according to the activity score and wait-and-see or surgery are widely chosen for patients in inactive phase. A great number of patients in inactive phase becoming refractory and reoccurring. Until now, the improvement of TAO is still be measured subjectively with low reliability and less accuracy. Multi-modal image is a new method to assess both the appearance and visual function of TAO and some of the indexes can be regarded as more apparent and stable in assessing the efficacy and prognosis of TAO. This perspective cohort study aims to evaluate the efficacy of immunosuppressive agents in TAO by multi-model image and function assessments.

Conditions

• Thyroid Associated Ophthalmopathy

Interventions

Type	Name	Description
DRUG	immunosuppressive agent	patients with TAO recruited in this study will administrated with immunosuppressive agent per day

Timeline

• Start date: 2021-10-15
• Primary completion: 2024-12-01
• Completion: 2025-12-01
• First posted: 2021-11-05
• Last updated: 2023-04-18

Locations

1 site across 1 country: China