Trials / Completed
CompletedNCT05109390
A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults
A Three-Part Phase 1 Study to Evaluate the Potential Drug Interaction Between ACH-0144471 and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adult Subjects
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 72 (actual)
- Sponsor
- Alexion Pharmaceuticals, Inc. · Industry
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This was a 3-part study with each part being an open-label, fixed-sequence, 2-period study in healthy adult participants.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Danicopan | Oral tablet. |
| DRUG | Cyclosporine | Oral capsule. |
| DRUG | Tacrolimus | Oral capsule. |
| DRUG | Calcium Carbonate | Chewable tablet. |
| DRUG | Aluminum/Magnesium Hydroxide/Simethicone | Chewable tablet. |
| DRUG | Omeprazole | Oral, delayed-release capsule. |
Timeline
- Start date
- 2018-07-27
- Primary completion
- 2018-10-17
- Completion
- 2018-10-17
- First posted
- 2021-11-05
- Last updated
- 2021-11-05
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT05109390. Inclusion in this directory is not an endorsement.